And according to this link, it has 6 causes. My users can send emails to other company employee's but cannot email to external addresses.
KB04422-A Red X appears in the message list after attempting to send an email message from the BlackBerry smartphone with an error "Desktop email program was unable to submit message"
However, I've gone through all 6 and none are incorrect!
the Router is working, the mailboxes are not full, the sendas is being inherited at the domain level , throttling policy is set and LDAP isn't failing!
Running BES 5.0 sp3(I know, a few behind, I'll be updating tonight), with Exchange 2010 sp2.
I'm thinking about doing the fix for LDAP to bypass MAPI and use LDAP for queries.. is this a good idea?