It will nuke everything including some 3rd party applications. Best to perform a backup first. There is a procedure on here to capture applications in the backup as well. It involves intercepting an application loader backup before it deletes itself by way of executing the switch device wizard. You grab the backup file that's created and never actually connect the second device. I don't recall which thread.
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Treat your password like your toothbrush. Don't let anybody else use it, and get a new one every six months.
Clifford Stoll
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