The number of Agents is determined by the either the Dispatcher or Controller service and has nothing to do with the mail platform that I am aware of. If you have Domino BES, then check the registry for the key and change to 6 and restart your services, in the off hours of course. It should work the same as Exchange. I've only seen Exchange BES use this as a fix to MAPI Worker Thread issues but it shouldn't be a permanent fix. Once the source of the Worker Thread issue is resolved you should no longer needed to have more then 5 Agents.
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