Care to give us anything more to go on to try and help you? Have you checked for the vendor.xml file again?
These are the steps.
1. Install Desktop Manager. (Looks like you've done that.)
2. Install OS to the PC in addition to DM. (Make sure the OS is still installed to the PC. If it's not, install it again. You can check in Desktop Manager by going to Help >About >Device Software Tab. It should list the OS 4.5.0.37 for the 8100. If it doesn't you'll need to install it.)
3. AFTER installing both 1 & 2, delete vendor.xml file from location mentioned above.
4. Plug in BB, open DM and run Application Loader. It should recognize the files on your BB.
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